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PEAKS AB 3.5
https://crackeddownload.com/product/peaks-ab-3-5/
PEAKS AB 3.5 Software New Features
PEAKS AB automates protein de novo antibody sequencing using liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) datasets from orthogonal enzyme digests. From confident de novo sequence tags, the full protein sequence is assembled using a weighted de Brujin graph1.
In peaks AB 3.5, the software package is equipped with additional tools to enhance sequencing accuracy, PTM characterisation and result presentation including:
Retention time prediction for isobaric differentiation.
Improved intact mass deconvolution algorithm.
lle/Leu differentiation by the signature w-ions included in sequence validation function.
Added support for in-depth O-glycan analysis.
Merged glycopeptides into peptide mapping view.
Support for timsTOF data
Improved UI and report.
In-Depth Glycan Profiling
In our previous PEAKS AB build we introduced N-linked glycan profiling. In addition to this, PEAKS AB 3.5 now supports identification and profiling of O-linked glycans. This tool performs in-depth glycan profiling for both N- and O-linked sites identified in the heavy and/or light chains of the antibody. In addition to accurate glycopeptides mapping to the assembled antibody sequence, enzyme-based glycan profiling displays the composition and relative abundance of each glycan at a selected glycosylation site. Glycan composition and structure annotation are provided within each glycopeptide spectrum and are based on glycan fragment ions that match to an O-linked or N-linked glycan databases. Accurate localisation of the glycan at each site is achieved by identifying fragment ions of glycan moieties associated with the peptide backbone.
O linked website
Retention Time Prediction to Differentiate Isobaric Residues
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